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Causes of death and health conditions · Mental and nervous system

Multiple sclerosis deaths in the UK

The Office for National Statistics recorded 1,402 deaths in England and Wales in 2025 where the underlying cause was Multiple sclerosis (ICD-10 G35). That was 71 more than in 2024 (1,331). Since 2001 the yearly figure has ranged from 887 (2001) to 1,474 (2023).

England and Wales, 2025
1,402
deaths registered · ONS
Age-standardised rate, 2025
2.3
per 100,000 people · ONS
Scotland, 2024
184
deaths registered · NRS
Northern Ireland, 2024
47
deaths registered · NISRA

Deaths each year in England and Wales

1,474887 2001 2025
Deaths registered in England and Wales from Multiple sclerosis, 2001 to 2025. Office for National Statistics.

Taking account of the population's size and age, the ONS age-standardised death rate was 2.3 per 100,000 people in 2025, 9.5% higher than in 2013 (2.1). For men it was 1.7 and for women 2.8.

Men accounted for 499 of the 2025 deaths and women for 903.

Multiple sclerosis, G35: deaths registered in England and Wales; rate per 100,000 from 2013.
YearAllMenWomenAge-standardised rate
20251,4024999032.3
20241,3314538782.2
20231,4745319432.5
20221,3954978982.4
20211,2414298122.1
20201,3464898572.4
20191,3704948762.4
20181,3724908822.5
20171,3284858432.4
20161,3204498712.4
20151,2954578382.4
20141,2024157872.3
20131,1003737272.1
20121,218439779–
20111,062388674–
20101,004354650–
20091,012339673–
20081,050369681–
20071,002375627–
2006933308625–
2005963350613–
2004887301586–
2003999335664–
2002923321602–
2001887296591–

Age at death

Of the 1,402 deaths in 2025 with an age recorded, 38.9% were of people aged 75 or over; the largest number, 446, was in the 65 to 74 age group.

Deaths by age at death, England and Wales.
Age2025: all2025: men2025: women2001: all
Under 150000
15 to 4420515102
45 to 64390155235400
65 to 74446164282219
75 to 84423151272141
85 and over123249925

Scotland

National Records of Scotland recorded 184 deaths from this cause in 2024 (52 men, 132 women).

Northern Ireland

NISRA's Registrar General figures give 47 deaths from this cause registered in Northern Ireland in 2024, against 40 in 2014.

Deaths registered in Northern Ireland. NISRA, Registrar General Annual Report, table 6.4b.
YearAllMenWomen
2024471928
2023411130
2022491831
2021421527
2020451728
2019351322
2018582632
2017481335
2016552233
2015561442
2014401723

How the figures are defined

Each death is counted once, under its underlying cause: the disease or injury that started the chain of events leading to death, as certified by a doctor or coroner and coded by the ONS to the International Classification of Diseases (ICD-10). This page uses the ONS grouping “Multiple sclerosis”, codes G35. Other conditions mentioned on a death certificate are not counted here.

Registration dates, the deaths left out, the age-standardised rate and the ONS's coding changes are explained under how these figures are compiled.

Related answers

More in mental and nervous system

Sources and receipts

ONS mortality extracts for codes G35, with SHA-256 fingerprints; the ONS, NRS and NISRA workbooks are listed with the other sources.

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